Box–Behnken experimental design for extraction of artemisinin from Artemisia annua and validation of the assay method
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چکیده
منابع مشابه
Examining The Extraction Of Artemisinin From Artemisia Annua Using Ultrasound
Artemisinin suppresses the life-cycle of the plasmodium parasite which causes malaria. It is found naturally occurring within the trichome glands of the Artemisia annua plant. Traditional methods for extracting artemisinin are time-consuming and have high environmental impact due to the temperatures and organic solvents which must be employed. Ultrasound decreases these through acoustic streami...
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The antimalarial artemisinin, the active principle of the plant Artemisia annua L., was extracted by Supercritical Fluid Extraction (SFE). Soxhlet extraction was studied as comparison processes. The extracts were analyzed by the indirect method GC-FID. The maximal extraction yield (1.82%DW) was obtained by SFE at T=40°C, P=200bar, CO2flow=4.5g/min, and 20% ethanol as modifier. The artemisinin e...
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اتانول کاربردهای متنوعی در صنایع لاستیک سازی، رنگسازی، حلالها ومکمل سوخت خودرو دارد. اتانول برخلاف نفت از جمله مواد تجدیدپذیر محسوب می شود که مشکلات زیست محیطی و آلودگی نیز ایجاد نمی کند. استفاده از اتانول به عنوان مکمل سوختخودروها از جمله مهمترین مصارف صنعتی این ماده بشمار می رود. با توجه به این موضوع تحقیق و توسعه در زمینه تولید اتانول با درجه خلوص بالا در سطح جهان، و نه تنها در کشور های پیشر...
construction and validation of the translation teacher competency test and the scale of students’ perceptions of translation teachers
the major purpose of this study was to develop the translation teacher competency test (ttct) and examine its construct and predictive validity. the present study was conducted in two phases: a qualitative phase as well as a quantitative phase. in the first phase of the study, the author attempted to find out the major areas of competency required for an academic translation teacher. the second...
Artemisia annua (Sweet Annie), Other Artemisia Species, Artemisinin, Artemisinin Derivatives, and Malaria
This paper reviews the use of whole-plant Artemisia annua (sweet Annie) as it pertains to malaria including history, chemistry, clinical efficacy, pharmacokinetics, dosing, safety, and resistance. Artemisinin, the sesquiterpene lactone found in the plant, and various semi-synthetic variants of it used as critical drugs around the world for malaria are discussed in comparison to the whole plant....
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ژورنال
عنوان ژورنال: Revista Brasileira de Farmacognosia
سال: 2017
ISSN: 0102-695X
DOI: 10.1016/j.bjp.2017.03.002